Placental Bed Disorders: Basic Science and its Translation to Obstetrics

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Robert Pijnenborg, Ivo Brosens, Roberto Romero
Cambridge University Press, 3. juuni 2010
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It is now recognized that defective placentation in the human is a cause of many pregnancy complications, such as spontaneous abortion, preterm labor and delivery, pre-eclampsia, intrauterine growth restriction, fetal death and abruptio placenta. These clinical disorders can often have long-term consequences into adulthood, causing cardiovascular disease, obesity and diabetes for the newborn as well as an increased risk of premature death in the mother. This is the first book to be entirely focused on the placental bed, bringing together the results of basic and clinical research in cell biology, immunology, endocrinology, pathology, genetics and imaging to consolidate in a single, informative source for investigators and clinicians. Its core aim is to explore new approaches and improve current clinical practice. This is essential reading for clinicians in obstetric, cardiovascular and reproductive medicine.
 

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Contents

Unraveling the anatomy 5 and pregnancy rate of in vitro fertilization treatment 85
5
Defective spiral artery remodeling
11
The search for susceptibility genes 174 Section 8 Translation
17
decidua trophoblast or and research models 109
22
Decidualization
29
Immune cells in the placental bed
41
Department of Medicine Obstetrics and Gynecology Women and Childrens Hospital
75
Boston MA USA Robert D Martin
109
Placental angiogenesis 52 Robert H Lane Robert A McKnight and Qi
149
Oxygen delivery at the deciduoplacental Section 6 Genetics
165
Division of Molecular and Vascular Medicine Salt Lake City
195
Carter David Haig
207
Angiogenic factors and preeclampsia
229
and
243
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About the author (2010)

Robert Pijnenborg is Professor, Department of Woman and Child, Katholieke Universiteit Leuven, Belgium.

Ivo Brosens is Emeritus Professor at the Katholieke Universiteit Leuven, Belgium.

Roberto Romero is Chief, Perinatology Research Branch, Program Director for Obstetrics and Perinatology and Professor of Molecular Obstetrics and Genetics, Wayne State University School of Medicine, Detroit, USA.

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