Ocular NeuroprotectionCRC Press, 15. juuli 2003 - 344 pages Many retinal and optic nerve disorders have no effective therapy, or are treated incompletely and with considerable side effects. Recent advances have suggested the significant benefits associated with neuroprotection - that is, when treatment strategies are directed to photoreceptors, retinal ganglion cells, or other neural targets. Enter Ocular N |
Contents
Chapter 1 Culture of Retinal Neurons | 1 |
Chapter 2 Crush Injury of the Optic Nerve | 13 |
Vein Cauterization | 23 |
Injecting Hypertonic Saline into Episcleral Veins | 31 |
Laser Photocoagulation of the Trabecular Meshwork | 47 |
Chapter 6 LightInduced Retinal Degeneration | 85 |
Chapter 7 Retinal Detachment | 109 |
Chapter 8 Retinal Ischemia | 129 |
Chapter 12 Ex Vivo and WholeMount Retinal Preparations | 205 |
Chapter 13 Detection of SingleCell Apoptosis | 225 |
Chapter 14 Imaging of Retinal Ganglion Cells | 241 |
Electroretinography | 249 |
Chapter 16 Evaluation of Visual Outcome | 273 |
Chapter 17 Clinical Trials in Neuroprotection | 291 |
Chapter 18 Regulatory Issues in Clinical Trials | 303 |
313 | |
Chapter 9 Drug Delivery | 153 |
Chapter 10 Recombinant Viral Vectors | 167 |
Chapter 11 Quantification of Retinal Cells | 189 |
Back Cover | 328 |
Other editions - View all
Common terms and phrases
addition allows amplitude analysis animals apoptosis appear applied assess axons blood brain cell culture changes clinical trials compared cone containing counting culture death degeneration density described determine developed disease drug effects elevated experimental experimental glaucoma experiments exposure expression factor Figure function gene glaucoma human identified imaging important increase induced injection injury intensity intraocular pressure Invest Ophthalmol involved ischemia labeling layer levels light damage loss measurements method monkeys needle neurons neuroprotection normal obtained occurs ocular Ophthalmol Vis Sci optic nerve patients pattern perimetry photoreceptor placed possible potential primate procedure produce recording response retinal detachment retinal ganglion cells RGCs saline Sample showed specific standard studies subjects technique tion tissue transgene treatment vectors vein vessels virus visual visual field