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in Experiments 1 and 2, contained 159, 150, 171, and 168 polynuclear leucocytes in 20 fields of the four specimens examined; the lung. 230 and 209; the liver, 38 and 35 respectively.

This experiment then shows a large increase in the number of the polynuclear leucocytes in the organs, as compared with what was found in the organs of the control animals.

But, as the injection of peptone causes not only a primary diminution but also a secondary augmentation in the number of leucocytes in the blood, it might be argued that this augmentation takes place at first in the organs, and that this might account for the increase found in Experiment No. 4.

To meet this objection the following experiment was made :

No. 5. Rabbit, 2 kilos. Blood from ear contained 9200 leucocytes, of which 47 per cent. or 4424, belonged to the polynuclear variety; 20 c.c. of a 10 per cent. peptone solution were now rapidly injected into the left jugular vein, and the animal killed five seconds after the injection.

The blood contained in the heart was at once examined, that in the left ventricle being found not to contain a single leucocyte of any kind whatever; that of the right only 166 per cubic millimetre, all told. It must be noted, however, that the leucocytes do not disappear from all parts of the circulation with this marvellous rapidity, as Experiment No. 7 will show.

The organs in this case were also found to contain a great excess of polynuclear leucocytes: the spleen, 174, 133, and 149; the lung, 230 and 221; the liver, 12 and 14.

I next tried the effect of first causing a leucocytosis, and then driving the white blood corpuscles out of the blood by peptone, in the belief that some proportionate increase in the number of the polynuclear leucocytes in the organs might be found.

No. 6. Rabbit, weight 2 kilos. Blood from ear contained 7800 leucocytes, of which 4290 belonged to the polynuclear variety.

Nineteen hours after the injection of 10 c.c. of a broth cultivation of anthrax, which had been sterilised by filtration through a Chamberland filter, the number of leucocytes in the blood taken from the ear had increased to 17,600, of which 11,264 were polynuclear. 20 e.c. of a 10 per cent. peptone solution were now injected into the jugular vein, and, five seconds afterwards, the animal killed. Blood from the left ventricle contained no leucocytes; that from the right ventricle only 1500 per cubic millimetre.

The spleen sections contained 223 and 218, the lung 251 and 247, the liver 12 and 10.

Experiment 7. Rabbit, 2 kilos. The blood taken from an earvein contained 14,300 white-blood corpuscles.

20 c.c. of a 10 per cent. peptone solution were injected into an

ear-vein, and, five seconds afterwards, the white-blood corpuscles in the opposite ear enumerated, when no diminution in their number was found. Eighteen hours after the injection an intense leucocytosis was found to have become developed, no fewer than 184,500 white blood corpuscles being found in each cubic millimetre of blood drawn from the ear.

Again, 20 c.c. of a 10 per cent. peptone solution were injected; this time by the left jugular vein, and, five seconds afterwards, the animal killed. The blood in the left ventricle contained 1000 white blood corpuscles per cubic millimetre, the right ventricle 3000, and the inferior vena cava in the lumbar region 5000.

Sections of the spleen contained 262 and 308, the lung 435, 325, and 348, and the liver 78 and 82.

Presenting, for the sake of clearness, the above facts in a tabular form, an average of the various numbers being set down, the contrast is striking.

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From the above table it is seen that the lung harbours a greater proportion of the leucocytes which have disappeared from the blood than any other organ. This may be accounted for by the fact that this organ is the first acted on by the peptone solution after its injection into the jugular vein,

Other organs, such as the kidney, supra-renals, and ovary, were found to contain so few leucocytes, either before or after the injection of peptone, that the results as regards them have been neglected.

I conclude from the above experiments that the injection of a solution of peptone into the circulation of rabbits does not cause, as has been asserted, a destruction of leucocytes, but merely a withdrawal of them into various organs, notably the lungs and spleen.

The Society then adjourned over the Easter Recess to Thursday, April 19.

Transactions.

Presents, March 15, 1894.

Berlin:-Gesellschaft für Erdkunde. Verhandlungen. Bd. XXI.
No. 1. 8vo. Berlin 1894.
The Society.
Bordeaux :-Société de Médecine et de Chirurgie. Mémoires et
Bulletins. 1892. Fasc. 3-4. 1893. Fasc.
Bordeaux 1893-94.

1-2. 8vo.

The Society.

Brünn :-Naturforschender Verein. Verhandlungen. Bd. XXXI. 8vo. Brünn 1893; Bericht der Meteorologischen Commission. No. 11. 8vo. Brünn 1893. The Society. Cambridge, Mass.:-Harvard College. Annual Reports of the President and Treasurer. 1892-93. 4vo. Cambridge 1894. The College.

Anno.

Catania:-Accademia Gioenia di Scienze Naturali. Atti.
LXX. 4to. Catania 1893; Bullettino. Fasc. 33-35. 8vo.
Catania 1893.

Kazan:-Imperial University.

The Academy.

[Two Medical Dissertations.]

The University.

The Director.

[Russian.] 8vo. Kazan 1893. Kew:-Royal Gardens. Bulletin of Miscellaneous Information. 1894. No. 87. 8vo. London. Leipsic :-Königl. Sächs. Gesellschaft der Wissenschaften. Berichte über die Verhandlungen (Math.-phys. Classe). 1893. Hefte 7-9. 8vo. Leipzig 1894. The Society. London :-Geologists' Association. Proceedings. Vol. XIII. Part 6. 8vo. London 1894. Photographic Society of Great Britain. tions. Vol. XVIII. No. 4. 8vo.

The Association. Journal and TransacLondon 1893.

The Society.

Society of Biblical Archæology.

Part 4. 8vo. London 1894.

Proceedings. Vol. XVI.
The Society.

Paris :-Ecole Normale Supérieure. Annales. Tome XI. No. 1.
4to. Paris 1894.
The School.
Rotterdam-Bataafsch Genootschap der Proefondervindelijke
Wijsbegeerte. Verhandelingen. Reeks 2. Deel IV. Stuk 1.
4to. Rotterdam 1893.
The Society.
Santiago: Sociedad Nacional de Mineria. Boletin. Año X. No.
62. 4to. Santiago de Chile 1893.
Vienna :-K. K. Geologische Reichsanstalt.
Nos. 15-18. 8vo. Wien 1893.
Washington:-U. S. Department of Agriculture.
Station Record. Vol. V. No. 5. 8vo.

The Society.

Verhandlungen. 1893.
The Institute.

Experiment

Washington 1894.

The Department.

Observations and Reports.

Calcutta-Meteorological Department, Government of India.
Meteorological Observations recorded at Seven Stations in
India. September, 1893. 4to.; Monthly Weather Review.
September, 1893. 4to. Calcutta 1894. The Department.
Sydney: Observatory. Meteorological Observations. September,
1893. 8vo.
The Observatory.

Journals.

Annaes de Sciencias Naturaes. Anno. I. No. 1. 8vo. Porto 1894. The Editor. Revue Médico-pharmaceutique. Année VII. No. 1. 4to. Constantinople 1894. The Editor.

Technology Quarterly. Vol. VI. No. 3. 8vo. Boston 1893. Massachusetts Institute of Technology.

Hale (G. E.) The Solar Faculæ. 8vo. London 1894.

The Author.

8vo. Bir

Mr. W. P. Marshall.

[Marshall (A. M.), F.R.S.]. [Biographical Notices. mingham 1894]. Schück (A.) Magnetische Beobachtungen an der Unterelbe, angestellt im Jahre 1893. 8vo. Hamburg 1894. The Author. Vogel (H. C.) Über das Spectrum von B Lyrae. 8vo. Berlin 1894.

The Author.

Photograph of the Indenture of Sir H. Davy, in the possession of the Royal Institution of Cornwall, Mr. John D. Enys.

Account of the appropriation of the sum of £4,000 (the Government Grant) annually voted by Parliament to the Royal Society, to be employed in aiding the Advancement of Science (continued from vol. liii, p. 321).

April 1, 1893, to March 31, 1894.

GENERAL FUND.

A. M. W. Downing, for the Expense of Computations for a New Edition of Taylor's Madras Catalogue of Stars

£ s. d.

100 0 0

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Brought forward....

W. G. Rhodes, for a Minute Study of the Electrical Temperature Coefficient of some Pure Metals, with the view of obtaining an Electrical Thermometer more reliable than the Platinum Thermometer....

W. S. Wilson, to Make and Experiment with an Instrument which is designed to find the Direct Intensity of Solar Radiation

Dr. S. Young, for the Determination of the Vapour Pressures and Molecular Volumes, both as Liquid and Saturated Vapour, of various Substances, from Low Temperatures to their Critical Points

....

Dr. Edridge Green, for Continuation of his Experiments on Colour-blindness .....

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Prof. C. V. Boys, for a Research on the Constant of Gravitation by a very Exact Method depending on the use of Quartz Fibres

G. Higgs, for Completing and Printing a Photographic Atlas of the Normal Solar Spectrum....

Dr. Schuster, for Assistance in Certain Numerical Calculations concerning Terrestrial Magnetism

E. H. Griffiths, for (1) a Comparison of Air, Mercury, and Platinum Determinations of Temperature; (2) Continuation of Investigation into the Capacity for Heat of Water at Different Temperatures....

A. Mallock, for the Measurement of the Constant of Viscosity of Fluids, and the Examination of the Conditions which lead to Instability in the Flow of Fluids past Solid Obstacles...

A. J. Herbertson, for an Investigation into the
Hygrometry of the Atmosphere at Different Altitudes

C. T. Heycock and F. H. Neville, for Continuation of
Experiments on Solutions of Metals in Metals.......
J. Walker, for an Investigation of the Affinity of
Weak Acids and Bases.....

50 0 0

50 0 0

50 0 0

60 0 0

50 0 0

100 0 0

70 0 0

20 0 0

......

...

S. U. Pickering, for further Research on the Nature of Solutions

50 0 0

W. P. Bloxam, for an Examination of the Compounds formed by Ammonium with Sulphur..

S. E. Linder and H. Picton, for an Investigation into the Connection between different Grades of Solu

50 0 0

tion..

20 0 0

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£835 0 0

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