Comparative Genomics: Basic and Applied Research

Front Cover
James R. Brown
CRC Press, 3. dets 2007 - 400 pages
When genomic research first came on the scene, much of the biomedical research community viewed it as a limited venture with limited potential. We now know that such an assessment was both highly premature and wonderfully inaccurate. In the last ten years, we've witnessed such remarkable acceleration in the merger of basic and applied genomic
 

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Contents

The Broad Horizons of Comparative Genomics
1
Chapter 2 Advances in Next Generation DNA Sequencing Technologies
13
Chapter 3 LargeScale Phylogenetic Reconstruction
29
Chapter 4 Comparative Genomics of Viruses Using Bioinformatics Tools
49
Chapter 5 Archaebacteria and the ProkaryotetoEukaryote Transition and the Role of Mitochondria Therein
73
Chapter 6 Comparative Genomics of Invertebrates
87
Chapter 7 Comparative Vertebrate Genomics
105
Chapter 8 Gaining Insight into Human Population Specific Selection Pressure
123
Chapter 12 Comparative Genomics in AIDS Research
219
Chapter 13 Detailed Comparisons of Cancer Genomes
245
Chapter 14 Comparative Cancer Epigenomics
261
Chapter 15 G ProteinCoupled Receptors and Comparative Genomics
281
Chapter 16 Comparative Toxicogenomics in Mechanistic and Predictive Toxicology
299
Chapter 17 Comparative Genomics and Crop Improvement
321
A Treasure Trove for Comparative Genomics
341
Index
363

Chapter 9 Comparative Genomics in Drug Discovery
157
Chapter 10 Comparative Genomics and the Development of Novel Antimicrobials
177
Chapter 11 Comparative Genomics and the Development of Antimalarial and Antiparasitic Therapeutics
193
Back cover
392
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